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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243aeace8fd0da2b1ee55442ec021c712d01dd0d236afb6186d411832926d911' 
  AND token = 'apRRJ32aCi+bbOjKlNVKjKudd+63yh3GpTTyIxlo+qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}