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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04a18578f506abc4d3ed7a9597d53535c082e52b568a66c1340a9a6b6f7a748c' 
  AND token = 'PFen4gfAhfSNYTaT9S5OMWZfVITq1FrdOdf6HhW/SNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}