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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fa3741bd0610ecb4c75d7a5ffe221c7d86e79da9b4e7a40d7ec6e71d4279fc6' 
  AND token = 'bu7AwzqrmgCLXCgYoiOXd5RZeZxKa1scVqYGcdjxIhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}