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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2230978ac22c853db1bb6565071c8ec5390ecdf34f88a7d1a4673f8d07cc28f9' 
  AND token = 'VEILOP3hprrnRnVoKdXvecgjyU0M6zq9gmYoKvSnneg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}