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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aac748689a0b3c05b1fc0a6f3c1eb595990694008961d68d65f2df25b7cfe64' 
  AND token = '1QtYyjFR8b5CU1lLc9w2palRSVLFywMFPWwbsh6xMnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}