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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04667f0285d91bb0ee1ef77c5b3c89a390ba915f7788b18f3dc2b28b92e3da7b' 
  AND token = '5KgcZWwibvNyui6CAj35npa8g6h9ODfthtmG01na/NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}