SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7acfb12accd81ef62f21bdbc25df38861da258e033641f574d03e2a4c59e7e6d' 
  AND token = 'Ta5o8lHK4q67wbQfUQ8+RQdM2aK1lKzjxYUKxIIQdKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}