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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78df443e5da6b2946aeda3108e949f1d5d54748314ea9d4d1c0a78248f31dbc' 
  AND token = 'VhLnP2VWUciCjE5Kgmm8ieLA79sPoqX2vbDrSfWr5Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}