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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105acbe644d1023230ebeaf24afd0fa042da0431285c0a27ba3b813417210a38' 
  AND token = 'afZyLAoS1BpkGMuiqgA+4Ca9i+yadEu47DFmBRBRiHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}