SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b74b03dd7d950c50fb27a1555e2e82567409d44b070af84735576ac0b34c3cc2' 
  AND token = '7G+TOT+5XklzA8PH1XRfsBaLTLI2cWmjVNsmq6zN7Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}