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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eb1e9c81baae6e7f31a82f7a4b03301cd86fa0a62386c09a6c27e890fff7e1f' 
  AND token = 'y2NmjKKMgxVymG+e3EMVYjTH/Szb+DSCBjGwUVcN0Wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}