SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7c258035cca2c2ee09a967234a93c7eaaa40d25bd76fc3820947a034a481b23' 
  AND token = '50/pwsjDeiTghJsRqVg4qi5k/TbnEjM6vWVEIatbNBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}