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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1537de0304c4c5333982d46da1846f5a612420e4da070d8b0397c4c459dc8357' 
  AND token = 'D9iA7Sz9ndoqIMhilzaOCkwbSjvNkKlPc4+VDf+/zuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}