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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888ad3aae1c77fc05db58006fb6380e5720c9966b425dd1eaaad1c8dbc50e05c' 
  AND token = 'iA5NMZ6JkvpILC3s73RJjIIAbpsHdcTNv5y/6+7VBo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}