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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c5686927af506f7890038ce5317ca5fa7ac18f8638d38a98d20e4dc2f0c083' 
  AND token = 'oIaUJM4k/InoWZNk4nHZ5htC0+3hpM0BqukAIFwO3hY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}