SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21e4ee390dde0b28e6dd1297492f09809e99e237f30ead5a174d025246d2f4f' 
  AND token = 'XGwv6yltLxfEsaRIeSl2bbs+HVfRkisjJHkyVTlOST4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}