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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68ea729dd21f1c28858e76ae4e8b0150021c2e02110dd96186c56f6f09024e4f' 
  AND token = 'iCooLFlXQRls+u3kUq921TUEi1/mVjXV7v/WVvjojm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}