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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c335e25b99b5fa3121b2d68018c66d84eaf01cc62aead92f14616ced903f167d' 
  AND token = '+TGVIy2H0/I+HcE9GXOf24SaIEMi0M13rB8cVYfSmwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}