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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd3f73605be59e7df03d13a54d9c46083d2cd9cefbe5608db311cf6163c6f34' 
  AND token = '6lgI9wloc7LgflTiGP3VSUEUPht0AbY8zyDd4hv4OMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}