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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2e0b2f867e637d0cca386c493f552fa1969d4d18ec3c29e8c799b5d74c428c' 
  AND token = 'S2R5xYqe+4a1lfDzkoyjYlbKPNI7hxD0BUhyMBMi7BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}