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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4295c54f8d6111b6eb009e16c3e50fdf0770bd5e757d555402ad29fb509794d' 
  AND token = '+wxwh6atL0y+4Yz3vjWuWFQzRrBgyfTQ4cwyVvg7VKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}