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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9c710045ecb9f6d3943dd7ca5183b1baded6f016f5b3fa8de23b800af3218d0' 
  AND token = 'nMkQMS4VAYTtcqDPVgULweeo2P+NDTvBp8GUPPAaCAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}