SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd222996351f2e705516fbfc00ccc9a03689d67297b84e47c2c1f0a77d21a1ba0' 
  AND token = 'DECVnU55jBWhajLi0ZT1thbgQN4Db723RayPhtaGf6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}