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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527e8127e841f9f8f833ee0ec22aad62a65681ccbbdb4b18b8355eac9ab8c776' 
  AND token = 'c67vw2b+hxqJ/cSU/C9aq8VUIT6nh5IgH65sFUlD0A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}