SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78664f65975079b3e2377df0711b382a26e5a1aa560626e1926d0598890476fd' 
  AND token = 'SBRX9aDZ+vFCXKy6CfDWotEjFARz0Biyr4pfhe2Qhvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}