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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2764ad3cd19ea0b94e9357d3dc9fa5b0868baeb58883b2a731aee2935f61cb' 
  AND token = 'CVgsxrMJ9cRVKzKy34okD8BXkm+SUmdMnu3F1zfA9Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}