SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60d9c57ff0f93589de4f4919b8514da3e2784319a8b96c46b295e43a323f20bd' 
  AND token = 'fIFunYA2GnZxrOkDBZ1PllBgZkzW9MUlD9XcEfg1td8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}