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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e857d4d5c59f4b23878cff58a79a03b8d78154a6397c4b83c5996db2f2c8870' 
  AND token = 'TD8IIBRYbRVY+f6oSUIMULUwepl/8LP0dP71z2eZImc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}