SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f7beca3ccf1bc474f597153cea8b1910ce9a61b66c7522b1da4d116fcc588f' 
  AND token = 'jtSe9P9xCcuVxFuiYxno2RccVjFowZk1sQuoUx7Mllk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}