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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a8619560cf0c09e76eb6e9547d4057c60c364c38ed601fbfd4593e7a816c98' 
  AND token = 'D6CI5wS2L4yUewrj+J4bIuFTXoPmUyG1qXnFUjPhOOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00080

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}