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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48af77f6b4a0db3a9b44c189055753bbc16c992f74780f5ff0fd898714cf66e5' 
  AND token = 'CDN1WUQ1scYhjDELdYpOtE1h8P6ly0aXn2hKtZxKTMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}