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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cad49d1c19d779cd39e34c87b7c81a7e8cb745040f9c2a7c66cb4b49eefa2b0' 
  AND token = 'MkS3xCjwfDeVNhDDKhI3kB2tm9+l4k+7QXzdA1yPSsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}