SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ecac979ce2160a90ce7d6bb007fca53c27ee95414719e0d7ce5cd6fc8d520d9' 
  AND token = 's6N45QRw0DNIMA9CXvWALMziwls8znisdI5Wz79YpZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}