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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a898da28fd0a007d25a803d3179e3376fd4b4e90b716c674df747a3acca5fa' 
  AND token = 'aqQ73uH5mHbMgOWSU4lkKI4GtQUo/GrSYzwA06xOQgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}