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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb2f08a482663e1d5cb129b45e3dc4edc7221ba1e76fe8da9dbb2c221c64034' 
  AND token = '5g79m5oHw7VFV7MWAJQcRf9Lf3KbkaQQYb+23ZzKIVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}