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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b25e8c38df15b7a9b01acf5f07a47758bf9d763082e71e63c531fbb907fcb52' 
  AND token = 'yicvpKxU4Epdpu4eL9RjHVR+JMibSJEjSrG7Ir9kYUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}