SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '626b8842fdaea1d26dd03e3f25c72f261d40e84998c29bc4fa11aff3730f3dcc' 
  AND token = 'nOR1D+yaPrrlF1NFwN9gI32YAsMY+vu0Wl5D844h6cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}