SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20d18f96d1ce46a212849f9138331e8c723124d4924a41cbdbbb055ec6fe0a0a' 
  AND token = 'tlxJrKpBPQGTeoij1YoAmvmi9E7k6qYRY8g12AoBV/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}