SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02b3812e2cdb78e2ced83e68d2669712d12003158bef3e301da89fdb8ccde866' 
  AND token = '1W/fHT5+wPYwEErGMKHmBXMCn/xnzmJY2zmm7h/6W+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}