SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741eb9a3683c98e04f954a8e37f1e709f6929ad1e90abf8f7b6af42e13c74269' 
  AND token = 'EYjSQbP9GXUco1KOHxUlC0AtWXq6tk2KTSJritgXfmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}