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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755625e6daa31f87f637543d62cc01aec7e233e4dd12e9ebcad21b3d5157ac3a' 
  AND token = 'cGhQySYtNQdIkVtkDkTqiT+ZopjP9k7BXuQC6lSFBI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}