SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3c76115a9b59b08f7e8a484a164666296a9767d2afa7bbca825e05d5c7e7795' 
  AND token = 'GPgOQXDI7lftIm4g5kDIzIG91bzo5C1Zwui5GNhhJEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}