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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed1464e4fe9ac620780182ad6902cb6e3f80c1b26ff927489f5c5ee276e2539' 
  AND token = 'mbiqX3X9pqdXH/IslL9tN4Gyh9Kr+T5bxH4P7JQKcIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}