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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65250452309cb7f5742e6faf504ed76af0f2369c7505dc74cd099ae5d5d2d980' 
  AND token = '4iNhiCFJHyQREGBrtjrB/wQNVVdMB4+TDzrdf+Lj6ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}