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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3f5921e6bf67129f96269d951874d8c277781e5477aeba8cb598a01d9c3c06' 
  AND token = 'hATT8BiXAZ53Zvd4Lpe4qBLLfy5NFh/PI7ACBIr2K5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}