SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3276d88bde56eea6ec8d9c2efd65148e20bca3dad9b404e5dc37c09b630b020f' 
  AND token = 'FNuQm+uzKVhc00caZ50qgvuEi/d1+HBZKcQQkr9+wfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}