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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '536ef3a082864e857f70b7efca05a04b9a7a60d877d3d257a21193e3a7b88949' 
  AND token = 'G0wVNoP9g9mYNLF02MroOhZlSaWU2ZHQAToi4/knJmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}