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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6b23c5351b0a27df1f5e163b0dff7730d36c7f42e3cf8574551a8ca19ebb49' 
  AND token = 'b8dPHJhNQzkePOmkgHKqNgEImVAL9/DGqnrb1R32z8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}