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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2011c2e6f91d1ebc3a76c1e5f9129577d8fd78b188d55ace10c086af251ebb41' 
  AND token = 'igwmoJ2Z+NXpdvIdBkQ0w4RT2FSAQKfEvmQA9uDUgAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}