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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffa2fa52fd41bd21d4a7f9f304de135294aaab79bdc4dc031ee939674aab9e85' 
  AND token = 'lyxXUUmbLAs9j5uek3TlR3Eh5jxGgrzoX21cEHtjVFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}